EyeProdb

Joint Shantou International Eye Centre of Shantou University and The Chinese University of Hong Kong

By gene

By phenotype

Gene : TYR

OMIM : 606933

UniProt : P14679

AmiGO : P14679

Phenotype : Albinism, oculocutaneous, type IA Albinism, oculocutaneous, type IB Skin/hair/eye pigmentation 3, blue/green eyes Skin/hair/eye pigmentation 3, light/dark/freckling skin Melanoma, cutaneous maligt, susceptibility to, 8

Predicted PDB	WT/mutant	Sequence length	AlphaFold2 pLDDT	RoseTTA B-factor
TYRE294K	Missense Mutation	511	91.8205_91.8136_91.7123_91.5878_91.5848	8.2264_8.2266_8.2268_8.2272_8.2272
TYRP406L	Missense Mutation	511	91.8191_91.5865_91.2564_91.1417_91.1184	8.2262_8.2264_8.2266_8.2266_8.2269
TYRWT	Wildtype	511	91.9667_91.864_91.7068_91.6385_91.452	8.2262_8.2263_8.2262_8.2277_8.2278