EyeProdb

Joint Shantou International Eye Centre of Shantou University and The Chinese University of Hong Kong

By gene

By phenotype

Gene : CRYBA1

OMIM : 123610

UniProt : P05813

AmiGO : P05813

Phenotype : Cataract 10, multiple types

Predicted PDB	WT/mutant	Sequence length	AlphaFold2 pLDDT	RoseTTA B-factor
CRYBA1C185EfsX33	Frameshift Mutation	216	74.1358_73.1312_72.9871_72.7084_71.9908	7.9233_7.9229_7.923_7.9234_7.9242
CRYBA1E197VfsX22	Frameshift Mutation	217	78.2635_77.7497_77.2482_77.2061_77.0345	7.9304_7.929_7.9306_7.931_7.9319
CRYBA1G91del	Deletion	214	87.7142_87.1423_86.7137_86.5712_86.4833	7.4808_7.4847_7.4876_7.4861_7.4865
CRYBA1Q203DfsX16	Frameshift Mutation	217	80.6792_80.1321_80.1132_79.2292_78.2633	7.5208_7.5191_7.5227_7.5234_7.5345
CRYBA1Q203X	Nonsense Mutation	202	85.7096_84.9987_84.269_84.1931_84.1326	7.8879_7.8891_7.8888_7.889_7.8893
CRYBA1R114C	Missense Mutation	215	87.7714_87.3871_87.3579_87.0819_86.9428	7.926_7.927_7.927_7.9268_7.9275
CRYBA1S209W	Missense Mutation	215	86.3081_85.8783_84.9054_84.36_84.3219	7.926_7.9265_7.9264_7.9264_7.9269
CRYBA1WT	Wildtype	215	87.5281_87.4058_87.0399_86.9622_86.8134	7.9267_7.9268_7.9274_7.9288_7.929