EyeProdb

Joint Shantou International Eye Centre of Shantou University and The Chinese University of Hong Kong

By gene

By phenotype

Gene : COL8A2

OMIM : 120252

UniProt : P25067

AmiGO : P25067

Phenotype : Corneal dystrophy, Fuchs endothelial, 1 Corneal dystrophy, posterior polymorphous 2

Predicted PDB	WT/mutant	Sequence length	AlphaFold2 pLDDT	RoseTTA B-factor
COL8A2Q455K	Missense Mutation	675	61.7692_61.137_59.3186_58.3484_55.9633	8.038_8.038_8.0381_8.038_8.038
COL8A2R304Q	Missense Mutation	675	61.683_60.5745_59.5682_59.1445_55.7912	8.038_8.0379_8.038_8.0381_8.0381
COL8A2WT	Wildtype	675	61.312_60.2538_60.1288_58.4811_56.9241	8.038_8.038_8.038_8.0381_8.0382